Azacitadine 100 mg Injection

About Azacitadine 100 mg Injection

Introduction to Azatend 100mg Injection

Azatend 100mg Injection for injection is used for treating adults with Myelodysplastic syndrome (MDS) and Acute myeloid leukemia (AML) if they are considered ineligible for stem cell transplant. It contains azacitidine as its active ingredient. In Myelodysplastic Syndrome, the bone marrow does not produce healthy blood cells due to its lack of function. Acute Myeloid Leukemia is a type of bone marrow cancer caused by the release of incompletely formed blood cells into the bloodstream.

Uses of Azatend 100mg Injection

• Treatment of Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Haemopoietic stem cell transplant
• Intermediate-2 and High-risk Myelodysplastic syndrome (MDS)

Therapeutic Effects of Azatend 100mg Injection

In MDS and AML, the development of tumor cells is caused by the process of transcriptional repression of various genes, which is due to hypermethylation of DNA. Transcriptional repression is a process where proteins bind directly or indirectly to DNA and control the activity of copying a specific gene or a set of genes. The active form of Azatend 100mg Injection binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.

Interaction of Azatend 100mg Injection with other drugs

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Azatend 100 mg injection and cause undesirable side effects.